An amino acid-containing building block
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Isomer(s)
30495Boc-Orn(Fmoc)-OH
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Fmoc-Orn(Boc)-OH

Item No. 30471

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N5-[(1,1-dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine
CAS Number
109425-55-0
Molecular Formula
C25H30N2O6
Formula Weight
454.5
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMF:PBS (pH 7.2) (1:5): 0.16 mg/mlDMSO: 10 mg/mlEthanol: 10 mg/ml
λmax
266 nm
SMILES
O=C(N[C@H](C(O)=O)CCCNC(OC(C)(C)C)=O)OCC1C(C=CC=C2)=C2C3=C1C=CC=C3
InChi Code
InChI=1S/C25H30N2O6/c1-25(2,3)33-23(30)26-14-8-13-21(22(28)29)27-24(31)32-15-20-18-11-6-4-9-16(18)17-10-5-7-12-19(17)20/h4-7,9-12,20-21H,8,13-15H2,1-3H3,(H,26,30)(H,27,31)(H,28,29)/t21-/m0/s1
InChi Key
JOOIZTMAHNLNHE-NRFANRHFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 mg

    $41

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    1 g

    $75

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    Product Description

    Fmoc-Orn(Boc)-OH is an ornithine-containing amino acid building block.1 It has been used to conjugate ornithine to GFP-labeled peptides, enhancing cell permeability when compared to unconjugated GFP-labeled peptides.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wender, P.A., Rothbard, J.B., Jessop, T.C., et al. Oligocarbamate molecular transporters: Design, synthesis, and biological evaluation of a new class of transporters for drug delivery. J. Am. Chem. Soc. 124(45), 13382-13383 (2002).

    2. Kumar, J., Yellepeddi, V.K., Davies, G.E., et al. Enhanced gene transfection efficiency by polyamidoamine (PAMAM) dendrimers modified with ornithine residues. Int. J. Pharm. 392(1-2), 294-303 (2010).