A heterocyclic building block
Related Products
Isomer(s)
304002-Amino-6-chloropurine
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2-Chloroadenine

Item No. 30474

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-chloro-9H-purin-6-amine
CAS Number
1839-18-5
Synonyms
  • 6-amino-2-chloropurine
  • 2-chloro-6-aminopurine
  • NSC 7362
Molecular Formula
C5H4ClN5
Formula Weight
169.6
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Ethanol: slightly soluble
λmax
265 nm
SMILES
NC1=C2C(N=CN2)=NC(Cl)=N1
InChi Code
InChI=1S/C5H4ClN5/c6-5-10-3(7)2-4(11-5)9-1-8-2/h1H,(H3,7,8,9,10,11)
InChi Key
HBJGQJWNMZDFKL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    250 mg

    $107

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    500 mg

    $129

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    1 g

    $235

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    Cayman Chemical
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    Product Description

    2-Chloroadenine is a heterocyclic building block that has been used in the synthesis of adenosine antimetabolites with antineoplastic activity.1 It is also the major catabolite of 2-chloro-2’-deoxyadenosine.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bauta, W.E., Schulmeier, B.E., Burke, B.J., et al. A new process for antineoplastic agent clofarabine. Org. Proc. Res. Dev. 8(6), 889-896 (2004).

    2. Bontemps, F., Delacauw, A., Cardoen, S., et al. Metabolism and cytotoxic effects of 2-chloroadenine, the major catabolite of 2-chloro-29-deoxyadenosine. Biochem. Pharmacol. 59(10), 1237-1243 (2000).