A building block
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2-Fluoro-4-iodo benzonitrile

Item No. 30483

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
137553-42-5
Synonyms
  • 4-Iodo-2-fluoro benzonitrile
Molecular Formula
C7H3FIN
Formula Weight
247.0
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2) (1:5): 0.16 mg/ml
λmax
255, 280, 289 nm
SMILES
IC1=CC=C(C#N)C(F)=C1
InChi Code
InChI=1S/C7H3FIN/c8-7-3-6(9)2-1-5(7)4-10/h1-3H
InChi Key
WHQVXHBSTRFRCE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

    $54

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    500 mg

    $102

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    1 g

    $190

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    Cayman Chemical
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    Product Description

    2-Fluoro-4-iodo benzonitrile is a building block.1,2 It has been used in the synthesis of L. infantum trypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors.1 2-Fluoro-4-iodo benzonitrile has also been used in the synthesis of transient receptor potential ankyrin 1 (TRPA1) antagonists.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Revuelto, A., Ruiz-Santaquiteria, M., de Lucio, H., et al. Pyrrolopyrimidine vs imidazole-phenyl-thiazole scaffolds in nonpeptidic dimerization inhibitors of Leishmania infantum trypanothione reductase. ACS Infect. Dis. 5(6), 873-891 (2019).

    2. Vallin, K.S., Sterky, K.J., Nyman, E., et al. N-1-Alkyl-2-oxo-2-aryl amides as novel antagonists of the TRPA1 receptor. Bioorg. Med. Chem. Lett. 22(17), 5485-5492 (2012).