An amino acid building block
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Nα-Boc-D-Histidine

Item No. 30501

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(1,1-dimethylethoxy)carbonyl]-D-histidine
CAS Number
50654-94-9
Synonyms
  • N-(tert-Butoxycarbonyl)-D-histidine
  • N-(t-Butoxycarbonyl)-D-histidine
  • Nα-tert-Butoxycarbonyl-D-histidine
Molecular Formula
C11H17N3O4
Formula Weight
255.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
λmax
214 nm
SMILES
OC([C@H](NC(OC(C)(C)C)=O)CC1=CN=CN1)=O
InChi Code
InChI=1S/C11H17N3O4/c1-11(2,3)18-10(17)14-8(9(15)16)4-7-5-12-6-13-7/h5-6,8H,4H2,1-3H3,(H,12,13)(H,14,17)(H,15,16)/t8-/m1/s1
InChi Key
AYMLQYFMYHISQO-MRVPVSSYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

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    Cayman Chemical
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    Product Description

    Nα-Boc-D-Histidine is an amino acid building block.1,2,3 It has been used in the synthesis of antimicrobial peptides, thyrotropin-releasing hormone enantiomers, and proteolysis-resistant peptide renin inhibitors.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chen, Y., Mant, C.T., and Hodges, R.S. Preparative reversed-phase high-performance liquid chromatography collection efficiency for an antimicrobial peptide on columns of varying diameters (1 mm to 9.4 mm I.D.). J. Chromatogr. A 1140(1-2), 112-120 (2007).

    2. Paruszewski, R., and Strzalkowska, M. New enzymatically stable inhibitors of human renin. Part II. Pol. J. Chem. 64(1-6), 149-156 (1990).

    3. Flouret, G., Morgan, R.J., Gendrich, R., et al. Synthesis of the thyrotropin-releasing hormone enantiomer and some diastereoisomers and in vitro studies of their biological activity. J. Med. Chem. 16(10), 1137-1140 (1973).