An amino acid building block
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Boc-Arg(Boc)2-OH

Item No. 30522

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(8S)-8-carboxy-4-[(1,1-dimethylethoxy)carbonyl]-3-imino-12,12-dimethyl-10-oxo-11-oxa-2,4,9-triazatridecanoic acid, 1-(1,1-dimethylethyl)ester
CAS Number
97745-69-2
Synonyms
  • Nα,NG,NG-Tri-tert-butyloxycarbonylarginine
Molecular Formula
C21H38N4O8
Formula Weight
474.6
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2) (1:5): 0.16 mg/ml
λmax
232 nm
SMILES
CC(C)(C)OC(NC(N(C(OC(C)(C)C)=O)CCC[C@@H](C(O)=O)NC(OC(C)(C)C)=O)=N)=O
InChi Code
InChI=1S/C21H38N4O8/c1-19(2,3)31-16(28)23-13(14(26)27)11-10-12-25(18(30)33-21(7,8)9)15(22)24-17(29)32-20(4,5)6/h13H,10-12H2,1-9H3,(H,23,28)(H,26,27)(H2,22,24,29)/t13-/m0/s1
InChi Key
DJIMINUZVZUBRO-ZDUSSCGKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

    $124

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    1 g

    $234

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    Cayman Chemical
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    Product Description

    Boc-Arg(Boc)2-OH is an amino acid building block and derivative of arginine.1,2 It has been used in the synthesis of amino acid prodrug forms of cytotoxic anthraquinones with anticancer activity.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Pozdnev, V.F. Nα,NG,NG-Tri-tert-butyloxycarbonylarginine. A new arginine derivative for peptide synthesis. Bioorganicheskaya Khimiya 12(8), 1013-1022 (1986).

    2. Anifowose, A., Yuan, Z., Yang, X., et al. Upregulation of p53 through Induction of MDM2 degradation: Amino acid prodrugs of anthraquinone analogs. Bioorg. Med. Chem. Lett. 30(2), 126786 (2020).