A thiol-reactive cross-linking agent
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Product Type

Biochemicals

N-(2-Aminoethyl)maleimide (trifluoroacetate salt)

Item No. 30530

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(2-aminoethyl)-1H-pyrrole-2,5-dione, 2,2,2-monotrifluoroacetate
CAS Number
146474-00-2
Synonyms
  • 2-Maleimidoethylamine
Molecular Formula
C6H8N2O2 • CF3COOH
Formula Weight
254.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
O=C(C=C1)N(CCN)C1=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C6H8N2O2.C2HF3O2/c7-3-4-8-5(9)1-2-6(8)10;3-2(4,5)1(6)7/h1-2H,3-4,7H2;(H,6,7)
InChi Key
YNHKVOGCDPODMT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

    $121

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    500 mg

    $229

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    1 g

    $334

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    Product Description

    N-(2-Aminoethyl)maleimide is a thiol-reactive cross-linking agent.1,2 It has been used in the synthesis of maleimide-functionalized heparin hydrogels in the development of growth factor delivery systems and radiotracers for thiol-mediated protein labelling.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nie, T., Baldwin, A.C., Yamaguchi, N., et al. Production of heparin-functionalized hydrogels for the development of responsive and controlled growth factor delivery systems. J. Control Release 122(3), 287-296 (2007).

    2. Kratz, H., Haeckel, A., Michel, R.P., et al. Straightforward thiol-mediated protein labelling with DTPA: Synthesis of a highly active 111In-annexin A5-DTPA tracer. EJNMMI Res. 2(1), 17 (2012).