A common reagent
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Chloramine-T (hydrate)

Item No. 30533

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-chloro-4-methyl-benzenesulfonamide, sodium salt, hydrate
CAS Number
149358-73-6
Molecular Formula
C7H7ClNO2S • Na [XH2O]
Formula Weight
227.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 15 mg/mlEthanol: 5 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
219 nm
SMILES
CC1=CC=C(S([N-]Cl)(=O)=O)C=C1.[Na+].O
InChi Code
InChI=1S/C7H7ClNO2S.Na.H2O/c1-6-2-4-7(5-3-6)12(10,11)9-8;;/h2-5H,1H3;;1H2/q-1;+1;
InChi Key
BXSDMMPOQRECKB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

    $36

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    Cayman Chemical
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    Product Description

    Chloramine-T is a common reagent in a variety of synthetic processes.1 It has been used as a reagent in aminohydroxylation and allylic amination reactions, as a nitrogen source for the aziridination of alkenes and olefins, and in the deprotection of thio groups in sulfur-containing compounds, among others. It has been used as a reagent in the synthesis of Factor Xa inhibitors.2 Chloramine-T (0.2% w/v) is also an antiseptic agent that is bactericidal against S. epidermidis, S. aureus, E. faecalis, E. coli, P. mirabilis, and E. cloacae.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Agnihotri, G. Chloramine-T (sodium N-chloro-p-toluenesulfonamide). Synlett 18, 2857-2858 (2005).

    2. Lam, P.Y.S., Clark, C.G., Li, R., et al. Structure-based design of novel guanidine/benzamidine mimics: Potent and orally bioavailable factor Xa inhibitors as novel anticoagulants. J. Med. Chem. 46(21), 4405-4418 (2003).

    3. Fuursted, K., Hjort, A., and L., K. Evaluation of bactericidal activity and lag of regrowth (postantibiotic effect) of five antiseptics on nine bacterial pathogens. J. Antimicrob. Chemother. 40(2), 221-226 (1997).