A synthetic intermediate
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(+)-Biotin-PEG3-amine

Item No. 30534

Technical Information
Formal Name
(3aS,4S,6aR)-N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide
CAS Number
359860-27-8
Synonyms
  • Amine-PEO3-biotin
Molecular Formula
C18H34N4O5S
Formula Weight
Purity
≥95%
A solid
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 20 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
O=C(N1)N[C@@]2([H])[C@]1([H])CS[C@H]2CCCCC(NCCOCCOCCOCCN)=O
InChi Code
InChI=1S/C18H34N4O5S/c19-5-7-25-9-11-27-12-10-26-8-6-20-16(23)4-2-1-3-15-17-14(13-28-15)21-18(24)22-17/h14-15,17H,1-13,19H2,(H,20,23)(H2,21,22,24)/t14-,15-,17-/m0/s1
InChi Key
KIJSBKNJFAUJFV-ZOBUZTSGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    (+)-Biotin-PEG3-amine is a synthetic intermediate.1 It has been used in the synthesis of biotinylated siderophores for whole-cell bacterial pull-down assays, as well as in the synthesis of protein-polysaccharide conjugate vaccines for S. pneumoniae.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hu, J., Ghosh, M., Miller, M.J., et alWhole-cell biosensing by siderophore-based molecular recognition and localized surface plasmon resonance. Anal. Methods 11(3), 296-302 (2019).

    2. Guo, M., Guo, X., Zhang, C., et alNovel pneumococcal protein-polysaccharide conjugate vaccine based on biotin-streptavidin. Infect. Immun. 90(1), (2022).