A building block
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Boc-NH-PEG3 Acid

Item No. 30536

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5,8,11-trioxa-2-azatridecanedioic acid, 1-(1,1-dimethylethyl) ester
CAS Number
462100-06-7
Molecular Formula
C13H25NO7
Formula Weight
307.3
Purity
≥95%
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 1 mg/mlEthanol: 30 mg/ml
SMILES
O=C(OC(C)(C)C)NCCOCCOCCOCC(O)=O
InChi Code
InChI=1S/C13H25NO7/c1-13(2,3)21-12(17)14-4-5-18-6-7-19-8-9-20-10-11(15)16/h4-10H2,1-3H3,(H,14,17)(H,15,16)
InChi Key
IFSMYFLQPDFUOI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 mg

    $41

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    50 mg

    $72

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    100 mg

    $134

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    250 mg

    $312

    Add
    Cayman Chemical
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    Product Description

    Boc-NH-PEG3 acid is a building block.1,2 It has been used as a linker in the synthesis of proteolysis-targeting chimeras (PROTACs) targeting MEK.1 It has also been used as a spacer in the synthesis of radiolabeled probes for dual labeling of tumor integrin αVβ3 and the gastrin-releasing peptide receptor (GRPR) in tumor tissue in vivo.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vollmer, S., Cunoosamy, D., Lv, H., et al. Design, synthesis, and biological evaluation of MEK PROTACs. J. Med. Chem. 63(1), 157-162 (2020).

    2. Liu, Z., Yan, Y., Chin, F.T., et al. Dual integrin and gastrin-releasing peptide receptor targeted tumor imaging using 18F-labeled PEGylated RGD-bombesin heterodimer 18F-FB-PEG3-Glu-RGD-BBN. J. Med. Chem. 52(2), 425-432 (2009).