A synthetic intermediate
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(S)-N-Boc-L-Homoserine ethyl ester

Item No. 30547

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(1,1-dimethylethoxy)carbonyl]-L-homoserine, ethyl ester
CAS Number
147325-09-5
Synonyms
  • N-Boc L-Homoserine ethyl ester
Molecular Formula
C11H21NO5
Formula Weight
247.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 25 mg/mlEthanol: 20 mg/mlPBS (pH 7.2): 3 mg/ml
SMILES
OCC[C@H](NC(OC(C)(C)C)=O)C(OCC)=O
InChi Code
InChI=1S/C11H21NO5/c1-5-16-9(14)8(6-7-13)12-10(15)17-11(2,3)4/h8,13H,5-7H2,1-4H3,(H,12,15)/t8-/m0/s1
InChi Key
HTGDPHFPHJVSEC-QMMMGPOBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $36

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    10 mg

    $68

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    25 mg

    $128

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    50 mg

    $236

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    Product Description

    (S)-N-Boc-L-homoserine ethyl ester is a synthetic intermediate in the synthesis of unsaturated caprolactams and monomer units for oxy-peptide nucleic acids from the starting material L-homoserine.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Janey, J.M., Orella, C.J., Njolito, E., et al. Raney-Co mediated reductive cyclization of an α,β-unsaturated nitrile. The Journal of Organic Chemistry 73(8), 3212-3217 (2008).

    2. Kuwahara, M., Arimitsu, M., and Sisido, M. Synthesis of δ-amino acids with an ether linkage in the main chain and nucleobases on the side chain as monomer units for oxy-peptide nucleic acids. Tetrahedron 55(33), 10067-10078 (1999).