An antiviral agent
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Enviroxime

Item No. 30552

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1E)-[2-amino-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-6-yl]phenyl-methanone oxime
CAS Number
72301-79-2
Synonyms
  • LY122772
Molecular Formula
C17H18N4O3S
Formula Weight
358.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: solubleMethanol: slightly, heated
SMILES
O/N=C(C1=CC=C(N=C(N)N2S(C(C)C)(=O)=O)C2=C1)\C3=CC=CC=C3
InChi Code
InChI=1S/C17H18N4O3S/c1-11(2)25(23,24)21-15-10-13(8-9-14(15)19-17(21)18)16(20-22)12-6-4-3-5-7-12/h3-11,22H,1-2H3,(H2,18,19)/b20-16+
InChi Key
IWKXBHQELWQLHF-CAPFRKAQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $41

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    10 mg

    $351

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    Cayman Chemical
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    Product Description

    Enviroxime is an antiviral agent.1 It inhibits coxsackievirus B3-, rhinovirus-, or poliovirus-induced plaque formation in HeLa monolayer cell cultures when used at concentrations of 0.1, 1, and 10 µg/ml.1 Enviroxime (1 µg/ml) inhibits production of poliovirus PV1 viral RNA in HeLa monolayer cell cultures. It reduces viral titers in DRAW macrophages infected with the DA strain of Theiler's murine encephalomyelitis virus.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Heinz, B.A., and Vance, L.M. The antiviral compound enviroxime targets the 3A coding region of rhinovirus and poliovirus. J. Virol. 69(7), 4189-4197 (1995).

    2. Steurbaut, S., Merckx, E., Rombaut, B., et al. Modulation of viral replication in macrophages persistently infected with the DA strain of Theiler’s murine encephalomyelitis virus. Virol. J. 5, 89 (2008).