An intermediate in glycogen metabolism
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α-D-Glucose-1-phosphate (sodium salt hydrate)

Item No. 30566

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(dihydrogen phosphate)α-D-glucopyranose tetrahydrate, disodium salt
CAS Number
150399-99-8
Synonyms
  • α-D-Glc 1-P
Molecular Formula
C6H11O9P • 2Na [4H2O]
Formula Weight
376.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OP([O-])([O-])=O)O1.[Na+].[Na+].O.O.O.O
InChi Code
InChI=1S/C6H13O9P.2Na.4H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;;;;/h2-10H,1H2,(H2,11,12,13);;;4*1H2/q;2*+1;;;;/p-2/t2-,3-,4+,5-,6-;;;;;;/m1....../s1
InChi Key
INXMOHFFQYLBED-CXWKFSMRSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    500 mg

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    Product Description

    α-D-Glucose-1-phosphate is an intermediate in glycogen metabolism.1,2 It is a precursor in the biosynthesis of UDP-glucose, the glucose donor in glycogen biosynthesis.2 α-D-Glucose-1-phosphate can be formed during glycogen breakdown via phosphorolytic cleavage of glycogen by glycogen phosphorylase.1 It can be converted to glucose-6-phosphate by phosphoglucomutase. α-D-Glucose-1-phosphate is combined with CTP by α-D-glucose-1-phosphate cytidylyltransferase to form CDP-glucose in the first step of CDP-D-tyvelose biosynthesis in S. typhi.3 Bacterial sucrose phosphorylase converts sucrose and phosphate into D-fructose and α-D-glucose-1-phosphate.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Berg, J.M., Tymoczko, J.L., and Stryer, L. Glycogen breakdown requires the interplay of several enzymes. Biochemistry (2002).

    2. Berg, J.M., Tymoczko, J.L., and Stryer, L. Glycogen is synthesized and degraded by different pathways. Biochemistry (2002).

    3. Koropatkin, N.M., and Holden, H.M. Molecular structure of ɑ-D-glucose-1-phosphate cytidylyltransferase from Salmonella typhi. The Journal of Biological Chemisty 279(42), 44023-44029 (2004).

    4. Goedl, C., Schwarz, A., Minani, A., et al. Recombinant sucrose phosphorylase from Leuconostoc mesenteroides: Characterization, kinetic studies of transglucosylation, and application of immobilised enzyme for production of ɑ-Ｄ-glucose 1-phosphate. J. Biotechnol. 129(1), 77-86 (2007).