A building block
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Ethyl 4-nitro-L-phenylalanine (hydrochloride)

Item No. 30615

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-nitro-L-phenylalanine, ethyl ester, monohydrochloride
CAS Number
58816-66-3
Molecular Formula
C11H14N2O4 • HCl
Formula Weight
274.7
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO:PBS (pH 7.2) (1:3): 0.25mg/mL
λmax
266 nm
SMILES
O=C(OCC)[C@@H](N)CC1=CC=C([N+]([O-])=O)C=C1.Cl
InChi Code
InChI=1S/C11H14N2O4.ClH/c1-2-17-11(14)10(12)7-8-3-5-9(6-4-8)13(15)16;/h3-6,10H,2,7,12H2,1H3;1H/t10-;/m0./s1
InChi Key
HHZUMTWHYNIFOC-PPHPATTJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 mg

    $90

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    1 g

    $168

    Add

    5 g

    $609

    Add
    Product Description

    Ethyl 4-nitro-L-phenylalanine is a building block.1,2 It has been used in the synthesis of chemokine (C-C motif) receptor 3 (CCR3) antagonists, as well as α4β1 (VLA-4) integrin antagonists.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. White, J.R., Lee, J.M., Dede, K., et al. Identification of potent, selective non-peptide CC chemokine receptor-3 antagonist that inhibits eotaxin-, eotaxin-2-, and monocyte chemotactic protein-4-induced eosinophil migration. The Journal of Biological Chemisty 275(47), 36626-36631 (2000).

    2. Phillips, D.J., Davenport, R.J., Demaude, T.A., et al. Imidazopyridines as VLA-4 integrin antagonists. Bioorg. Med. Chem. Lett. 18(14), 4146-4149 (2008).