An Analytical Reference Material of chloroquine
Features
  • This product is qualified as a Reference Material that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
Related Products
Labeled Version(s)
29079Chloroquine-d5 (phosphate)
Research Tool(s)
14194Chloroquine (phosphate)
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Chloroquine (phosphate)

Item No. 30708

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine, diphosphate
CAS Number
50-63-5
Synonyms
  • DL-Chloroquine
  • NSC 14050
Molecular Formula
C18H26ClN3 • 2H3PO4
Formula Weight
515.9
Purity
≥98%
Formulation (Request formulation change)
A neat solid
SMILES
ClC1=CC=C2C(N=CC=C2NC(C)CCCN(CC)CC)=C1.O=P(O)(O)O.O=P(O)(O)O
InChi Code
InChI=1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)
InChi Key
QKICWELGRMTQCR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $49

    Add

    5 mg

    $120

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Chloroquine (phosphate) (Item No. 30708) is an analytical reference material categorized as an antimalarial, anti-inflammatory, and antiviral agent.1,2,3 Chloroquine prevents infection by severe acute respiratory coronavirus 2 (SARS-CoV-2) in vitro.3 Counterfeit chloroquine has been seized by law enforcement during the COVID-19 pandemic.4 Formulations containing chloroquine have been associated with fatal overdoses.5,6 This product is intended for use in analytical research applications. This product is also available as a general research tool (Item No. 14194).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sidhu, A.B.S., Verdier-Pinard, D., and Fidock, D.A. Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations. Science 298(5591), 210-213 (2002).

    2. Plantone, D., and Koudriavtseva, T. Current and future use of chloroquine and hydroxychloroquine in infectious, immune, neoplastic, and neurological diseases: A mini-review. Clin. Drug Investig. 38(8), 653-671 (2018).

    3. Wang, M., Cao, R., Zhang, L., et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 30(3), 269-271 (2020).

    4. Schneider, M., and Nam, N.H.T. Africa and counterfeit pharmaceuticals in the times of COVID-19. J. Intellect. Prop. Law 15(6), 417-418 (2020).

    5. Queen, H.F., Tapfumaneyi, C., and Lewis, R.J. The rising incidence of serious chloroquine overdose in Harare, Zimbabwe: emergency department surveillance in the developing world. Trop. Doct. 29(3), 139-141 (1999).

    6. Keller, T., Schneider, A., Lamprecht, R., et al. Fatal chloroquine intoxication. Forensic Sci. Int. 96(1), 21-28 (1998).

    Product Citations

    Du, W., Gu, M., Hu, M., et al. Lysosomal Zn2+ release triggers rapid, mitochondria-mediated, non-apoptotic cell death in metastatic melanoma. Cell Rep. 37(3), 109848 (2021).