A reactive probe for derivatization of primary and secondary amines
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AQC

Item No. 30877

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-6-quinolinyl-carbamic acid, 2,5-dioxo-1-pyrrolidinyl ester
CAS Number
148757-94-2
Synonyms
  • 6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate
Molecular Formula
C14H11N3O4
Formula Weight
285.3
Purity
≥95%
Emission
398 nm (for derivatized polyamines)
Excitation
248 nm (for derivatized polyamines)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 5 mg/mlDMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
λmax
211, 242 nm
SMILES
O=C(ON1C(CCC1=O)=O)NC2=CC3=C(C=C2)N=CC=C3
InChi Code
InChI=1S/C14H11N3O4/c18-12-5-6-13(19)17(12)21-14(20)16-10-3-4-11-9(8-10)2-1-7-15-11/h1-4,7-8H,5-6H2,(H,16,20)
InChi Key
LINZYZMEBMKKIT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $97

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    50 mg

    $174

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    100 mg

    $311

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    250 mg

    $678

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    Product Description

    AQC is a reactive probe for the pre-column derivatization of primary and secondary amines, including those found in amino acids, peptides, proteins, and polyamines.1,2 It forms stable and highly fluorescent derivatives and has been used for chromatographic separation and analysis of derivatized amino acids and polyamines.1,2,3 AQC-derivatized polyamines display excitation/emission maxima of 248/398 nm, respectively.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Cohen, S.A. Quantitation of amino acids as 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate derivatives. J. Chromatogr. Lib. 70, 242-267 (2005).

    2. Weiss, T.S. HPLC of biogenic amines as 6-aminoquinolyl-N-hydroxysuccinimidyl derivatives. J. Chromatogr. Lib. 70, 502-523 (2005).

    3. Pawlowska, M., Chen, S., and Armstrong, D.W. Enantiomeric separation of fluorescent, 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, tagged amino acids. J. Chromatogr. A 641(2), 257-265 (1993).