A coumarin derivative
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7-Hydroxy-4-methyl-8-nitrocoumarin

Item No. 30900

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
7-hydroxy-4-methyl-8-nitro-2H-1-benzopyran-2-one
CAS Number
19037-69-5
Synonyms
  • 4-methyl-8-nitro-Umbelliferone
  • NSC 382373
Molecular Formula
C10H7NO5
Formula Weight
221.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS (pH 7.2) (1:2): 0.33 mg/mlDMSO: 10 mg/ml
λmax
215, 319 nm
SMILES
O=C1C=C(C)C(C=CC(O)=C2[N+]([O-])=O)=C2O1
InChi Code
InChI=1S/C10H7NO5/c1-5-4-8(13)16-10-6(5)2-3-7(12)9(10)11(14)15/h2-4,12H,1H3
InChi Key
BGUBUSIGKOWDPO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    500 mg

    $41

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    Product Description

    7-Hydroxy-4-methyl-8-nitrocoumarin is a coumarin derivative with antibacterial and antioxidant activities.1,2 It is active against S. aureus and E. coli in a disc assay when used at concentrations of 50 and 100 µg/disc.1 7-Hydroxy-4-methyl-8-nitrocoumarin inhibits NADPH-dependent lipid peroxidation in rat liver microsomes.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sahoo, S.S., Shukla, S., Nandy, S., et al. Synthesis of novel coumarin derivatives and its biological evaluations. Eur. J. Exp. Biol. 2(4), 899-908 (2012).

    2. Tyagi, Y.K., Kuma, A., Raj, H.G., et al. Synthesis of novel amino and acetyl amino-4-methylcoumarins and evaluation of their antioxidant activity. Eur. J. Med. Chem. 40(4), 413-420 (2005).