An internal standard for the quantification of CoQ10
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Unlabeled Version(s)
11506Coenzyme Q10
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Coenzyme Q10-d6

Item No. 30958

Technical Information
Formal Name
(all-E)-2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-di(methoxy-d3)-3-methyl-2,5-cyclohexadiene-1,4-dione
CAS Number
110971-02-3
Synonyms
  • CoQ10-d6
  • Ubidecarenone-d6
  • Ubiquinone-10-d6
  • Ubiquinone Q10-d6
Molecular Formula
C59H84D6O4
Formula Weight
Purity
≥99% deuterated forms (d1-d6)
A solid
Acetonitrile: SolubleDMSO: SolubleMethanol: SolubleWater: Soluble
SMILES
O=C(C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)=C1C)C(OC([2H])([2H])[2H])=C(OC([2H])([2H])[2H])C1=O
InChi Code
InChI=1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+/i13D3,14D3
InChi Key
ACTIUHUUMQJHFO-YDQRCUKRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    Coenzyme Q10-d6 (CoQ10-d6) is intended for use as an internal standard for the quantification of CoQ10 (Item No. 11506) by GC- or LC-MS. CoQ10 is a naturally occurring quinone found throughout the body in cell membranes, primarily in mitochondrial membranes, with highest concentrations in the heart, lungs, liver, kidneys, spleen, pancreas, and adrenal glands.1 It is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP.2 In its reduced form, CoQ10 acts as an antioxidant, preventing the formation of reactive oxygen species.2 CoQ10 deficiencies have been associated with heart failure, hypertension, parkinsonism, mitochondrial encephalomyopathies, and other chronic diseases.3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Saini, R. Coenzyme Q10: The essential nutrient. J. Pharm. Bioallied Sci. 3(3), 466-467 (2011).

    2. Crane, F.L. Biochemical functions of coenzyme Q10. J. Am. Coll. Nutr. 20(6), 591-598 (2001).

    3. Wyman, M., Leonard, M., and Morledge, T. Coenzyme Q10: A therapy for hypertension and statin-induced myalgia? Cleve. Clin. J. Med. 77(7), 435-442 (2010).

    4. Quinzii, C.M., and Hirano, M. Primary and secondary CoQ10 deficiencies in humans. BioFactors 37(5), 361-365 (2011).