An internal standard for the quantification of prostaglandin B2
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Unlabeled Version(s)
11210Prostaglandin B2
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Prostaglandin B2-d4

Item No. 311210

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9-oxo-15S-hydroxy-prosta-5Z,8(12),13E-trien-1-oic-3,3,4,4-d4 acid
CAS Number
211105-23-6
Synonyms
  • PGB2-d4
Molecular Formula
C20H26D4O4
Formula Weight
338.5
Purity
≥99% deuterated forms (d1-d4)
Formulation
A 500 µg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: >75 mg/ml (from PGB2)DMSO: >50 mg/ml (from PGB2)Ethanol: >100 mg/ml (from PGB2)PBS pH 7.2: >2 mg/ml (from PGB2)
λmax
278 nm
SMILES
O=C1C(C/C=C\C([2H])([2H])C([2H])([2H])CC(O)=O)=C(/C=C/[C@@H](O)CCCCC)CC1
InChi Code
InChI=1S/C20H30O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h4,7,12,14,17,21H,2-3,5-6,8-11,13,15H2,1H3,(H,23,24)/b7-4-,14-12+/t17-/m0/s1/i5D2,8D2
InChi Key
PRFXRIUZNKLRHM-GKNRUGNGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    50 µg

    $63

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    100 µg

    $118

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    500 µg

    $481

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    1 mg

    $842

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    Product Description

    Prostaglandin B2 (PGB2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGB2 by GC- or LC-mass spectrometry. PGB2 is a non-enzymatic dehydration product resulting from the treatment of PGE2 or PGA2 with strong base. It has weak agonist activity on TP receptors and can increase pulmonary blood pressure in the rabbit at relatively high doses (5 mg/kg).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, F., Orr, J.A., and Wu, J.Y. Prostaglandin B2-induced pulmonary hypertension is mediated by TXA2/PGH2 receptor stimulation. Am. J. Physiol. 1040, L602-L607 (1994).

    Product Citations

    Rhodes, L.E., Gledhill, K., Masoodi, M., et al. The sunburn response in human skin is characterized by sequential eicosanoid profiles that may mediate its early and late phases. FASEB J. 23(11), 3947-3956 (2009).