A peptide fragment of the laminin β1 chain
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Laminin (925-933)

Item No. 31141

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-cysteinyl-L-α-aspartyl-L-prolylglycyl-L-tyrosyl-L-isoleucylglycyl-L-seryl-L-arginine
CAS Number
110590-60-8
Synonyms
  • CDPGYIGSR
  • Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg
Molecular Formula
C40H62N12O14S
Formula Weight
967.1
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
O=C([C@H]1N(C([C@H](CC(O)=O)NC([C@@H](N)CS)=O)=O)CCC1)NCC(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(NCC(N[C@@H](CO)C(NC(CCCNC(N)=N)C(O)=O)=O)=O)=O)[C@@H](C)CC)=O)=O
InChi Code
InChI=1S/C40H62N12O14S/c1-3-20(2)32(37(63)46-17-30(56)48-27(18-53)35(61)49-24(39(65)66)6-4-12-44-40(42)43)51-34(60)25(14-21-8-10-22(54)11-9-21)47-29(55)16-45-36(62)28-7-5-13-52(28)38(64)26(15-31(57)58)50-33(59)23(41)19-67/h8-11,20,23-28,32,53-54,67H,3-7,12-19,41H2,1-2H3,(H,45,62)(H,46,63)(H,47,55)(H,48,56)(H,49,61)(H,50,59)(H,51,60)(H,57,58)(H,65,66)(H4,42,43,44)/t20-,23-,24?,25-,26-,27-,28-,32-/m0/s1
InChi Key
NGBBIWFVAWMQKZ-RMYNKKRNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $69

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    5 mg

    $297

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    10 mg

    $525

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    Product Description

    Laminin (925-933) is a peptide fragment corresponding to the laminin β1 chain.1 It binds to the laminin receptor when used at a concentration of 1 mg/ml. Laminin (925-933) stimulates the attachment of HT-1080 and CHO cells to culture plates when used at concentrations of 100 and 300 µg/ml. It induces chemotaxis of, as well as inhibits chemotaxis induced by full-length laminin, but not fibronectin, in B16/F10 murine melanoma cells. Laminin (925-933) conjugated to an agarose hydrogel backbone enhances neurite outgrowth in isolated chick embryo dorsal root ganglia and PC12 cells.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Graf, J., Iwamoto, Y., Sasaki, M., et al. Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding. Cell 48(6), 989-996 (1987).

    2. Bellamkonda, R., Ranieri, J.P., and Aebischer, P. Laminin oligopeptide derivatized agarose gels allow three-dimensional neurite extension in vitro. J. Neurosci. Res. 41(4), 501-509 (1995).