An internal standard for the quantification of 15-HEPE
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Unlabeled Version(s)
3271015(S)-HEPE
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15(S)-HEPE-d5

Item No. 31221

Technical Information
Formal Name
15(S)-hydroxy-5Z,8Z,11Z,13E,17Z-eicosapentaenoic-19,19,20,20,20-d5 acid
CAS Number
2750534-74-6
Synonyms
  • 15(S)-hydroxy Eicosapentaenoic Acid-d5
  • 15(S)-hydroxy EPA-d5
Molecular Formula
C20H25D5O3
Formula Weight
Purity
≥99% deuterated forms (d1-d5)
Formulation
A 100 µg/ml solution in ethanol
0.1 M Na2CO3: 2 mg/mlDMF: solubleDMSO: solubleEthanol: 1 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
237 nm
SMILES
O[C@@H](C/C=C\C([2H])([2H])C([2H])([2H])[2H])/C=C/C=C\C/C=C\C/C=C\CCCC(O)=O
InChi Code
InChI=1S/C20H30O3/c1-2-3-13-16-19(21)17-14-11-9-7-5-4-6-8-10-12-15-18-20(22)23/h3-5,8-11,13-14,17,19,21H,2,6-7,12,15-16,18H2,1H3,(H,22,23)/b5-4-,10-8-,11-9-,13-3-,17-14+/t19-/m0/s1/i1D3,2D2
InChi Key
WLKCSMCLEKGITB-SUTOMXFYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    15(S)-HEPE-d5 is intended for use as an internal standard for the quantification of 15-HEPE by GC- or LC-MS. (±)-15-HEPE and 15(S)-HEPE are formed via non-enzymatic and 15-lipoxygenase-mediated oxidation of eicosapentaenoic acid (Item Nos. 90110 | 90110.1 | 21908), respectively.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Miller, C., Yamaguchi, R.Y., and Ziboh, V.A. Guinea pig epidermis generates putative anti-inflammatory metabolites from fish oil polyunsaturated fatty acids. Lipids 24(12), 998-1003 (1989).

    2. Tan, L., Xin, X., Zhai, L., et alDrosophila fed ARA and EPA yields eicosanoids, 15S-hydroxy-5Z,8Z, 11Z, 13E-eicosatetraenoic acid, and 15S-hydroxy-5Z,8Z,11Z,13E,17Z-eicosapentaenoic acid. Lipids 51(4), 435-449 (2016).