An isomer of vitamin D3
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5,6-trans-Vitamin D3

Item No. 31225

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1S,3E)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexanol
CAS Number
22350-41-0
Synonyms
  • 5,6-trans-Cholecalciferol
Molecular Formula
C27H44O
Formula Weight
384.6
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 3 mg/mlEthanol: 30 mg/ml
λmax
272 nm
SMILES
C=C(CC[C@H](O)C/1)C1=C\C=C2CCC[C@@]3(C)[C@@]/2([H])CC[C@]3([H])[C@@H](CCCC(C)C)C
InChi Code
InChI=1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13+/t21-,24+,25-,26+,27-/m1/s1
InChi Key
QYSXJUFSXHHAJI-FVUVGDFOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $77

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    5 mg

    $339

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    10 mg

    $561

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    Product Description

    5,6-trans-Vitamin D3 is an isomer of vitamin D3 (Item No. 11792).1 In vivo, 5,6-trans-vitamin D3 (1, 3, and 10 µg/day) increases tibia ash weight and bone mineralization in vitamin D-deficient chicks. 5,6-trans-Vitamin D3 (25 µg/animal) induces intestinal calcium transport and bone calcium mobilization in anephric rats fed a low-calcium and vitamin D-deficient diet.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Boris, A., Hurley, J.F., and Trmal, T. Relative activities of some metabolites and analogs of cholecalciferol in stimulation of tibia ash weight in chicks otherwise deprived of vitamin D. J. Nutr. 107(2), 194-198 (1977).

    2. Holick, M.F., Garabedian, M., and DeLuca, H.F. 5,6-Trans isomers of cholecalciferol and 25-hydroxycholecalciferol. Substitutes for 1,25-dihydroxycholecalciferol in anephric animals. Biochemistry 11(14), 2715-2719 (1972).