An intermediate in the biosynthesis of thymidylate
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Product Type

Biochemicals

(6R,S)-5,10-Methenyl-5,6,7,8-tetrahydrofolic Acid (chloride)

Item No. 31333

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-amino-8-[4-[[[(1S)-1,3-dicarboxypropyl]amino]carbonyl]phenyl]-1,2,5,6,6aR,7-hexahydro-1-oxo-imidazo[1,5-f]pteridinium, monochloride
CAS Number
65981-90-0
Synonyms
  • Anhydroleucovorin
  • 6R-N5-N10-methylene-5,6,7,8-tetrahydrofolate
Molecular Formula
C20H22N7O6 • Cl
Formula Weight
491.9
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
λmax
370 nm
SMILES
O=C1C2=C(NC[C@@]3([H])N2C=[N+](C4=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C4)C3)NC(N)=N1.[Cl-]
InChi Code
InChI=1S/C20H21N7O6.ClH/c21-20-24-16-15(18(31)25-20)27-9-26(8-12(27)7-22-16)11-3-1-10(2-4-11)17(30)23-13(19(32)33)5-6-14(28)29;/h1-4,9,12-13H,5-8H2,(H6-,21,22,23,24,25,28,29,30,31,32,33);1H/t12-,13+;/m1./s1
InChi Key
NDMWNIVQVBEIJX-KZCZEQIWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

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    Product Description

    (6R,S)-5,10-Methenyl-5,6,7,8-tetrahydrofolic acid is an intermediate in the biosynthesis of thymidylate.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Karunaratne, K., Luedtke, N., Quinn, D.M., et al. Flavin-dependent thymidylate synthase: N5 of flavin as a Methylene carrier. Arch. Biochem. Biophys. 632, 11-19 (2017).