An alkaloid with antimalarial activity
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Noracronycine

Item No. 31336

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,12-dihydro-6-hydroxy-3,3,12-trimethyl-7H-pyrano[2,3-c]acridin-7-one
CAS Number
13161-79-0
Synonyms
  • NSC 103005
Molecular Formula
C19H17NO3
Formula Weight
307.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: Slightly Soluble: 0.1-1 mg/ml
SMILES
CC(C=C1)(C)OC2=C1C3=C(C(O)=C2)C(C4=CC=CC=C4N3C)=O
InChi Code
InChI=1S/C19H17NO3/c1-19(2)9-8-12-15(23-19)10-14(21)16-17(12)20(3)13-7-5-4-6-11(13)18(16)22/h4-10,21H,1-3H3
InChi Key
CBXBWBNEFPNSDO-UHFFFAOYSA-N
Origin
Plant/Acronychia baueri.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $229

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    $905

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    Cayman Chemical
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    Product Description

    Noracronycine is an alkaloid originally isolated from G. pentaphylla that has antimalarial activity.1,2 It is active against P. yoelii when used at a concentration of 10 µg/ml.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Govindachari, T.R., Pai, B.R., and Subramaniam, P.S. Alkaloids of Glycosmis pentaphylla (Retz.) correa. Tetrahedron 22(10), 3245-3252 (1966).

    2. Fujioka, H., Nishiyama, Y., Furukawa, H., et al. In vitro and in vivo activities of atalaphillinine and related acridone alkaloids against rodent malaria. Antimicrob. Agents Chemother. 33(1), 6-9 (1989).