A synthetic peptide corresponding to an integrin cell adhesion sequence
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Product Categories

Product Type

Biochemicals
Peptides

Research Area

Cell Biology
ECM & Adhesion Molecules

Arg-Gly-Asp (trifluoroacetate salt)

Item No. 31369

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(N-L-arginylglycyl)-L-aspartic acid, trifluoroacetate salt
CAS Number
120103-89-1
Synonyms
  • RGD
Molecular Formula
C12H22N6O6 • XCF3COOH
Formula Weight
346.3
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
N=C(N)NCCC[C@H](N)C(NCC(N[C@H](C(O)=O)CC(O)=O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C12H22N6O6.C2HF3O2/c13-6(2-1-3-16-12(14)15)10(22)17-5-8(19)18-7(11(23)24)4-9(20)21;3-2(4,5)1(6)7/h6-7H,1-5,13H2,(H,17,22)(H,18,19)(H,20,21)(H,23,24)(H4,14,15,16);(H,6,7)/t6-,7-;/m0./s1
InChi Key
FBPDETPEHPAQDC-LEUCUCNGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $81

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    10 mg

    $128

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    25 mg

    $239

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    50 mg

    $436

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    Product Description

    Arg-Gly-Asp (RGD) is a synthetic peptide corresponding to the cell adhesion sequence for the integrins αVβ1, αVβ3, αVβ5, αVβ6, αVβ8, α8β1, and α5β1.1,2 It is a component of radioligands and peptidomimetics that have been used in the study of integrin expression and activity in vivo.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ruoslahti, E. RGD and other recognition sequences for integrins. Annu. Rev. Cell Dev. Biol. 12, 697-715 (1996).

    2. Danhier, F., Le Breton, A., and Préat, V. RGD-based strategies to target alpha(v) beta(3) integrin in cancer therapy and diagnosis. Mol. Pharm. 9(11), 2961-2973 (2012).

    3. Schottelius, M., Laufer, B., Kessler, H., et al. Ligands for mapping αvβ3-integrin expression in vivo. Acc. Chem. Res. 42(7), 969-980 (2009).