A γ-lactone microbial metabolite
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Product Categories

Product Type

Biochemicals
Natural Products
Microbial Metabolites

Research Area

Cancer

Acetomycin

Item No. 31410

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3S,4S,5R)-3-acetyl-5-(acetyloxy)dihydro-3,4-dimethyl-2(3H)-furanone
CAS Number
510-18-9
Synonyms
  • (–)-Acetomycin
  • NSC 350598
Molecular Formula
C10H14O5
Formula Weight
214.2
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleMethanol: Soluble
SMILES
O=C(C)O[C@@H]([C@@H](C)[C@@]1(C)C(C)=O)OC1=O
InChi Code
InChI=1S/C10H14O5/c1-5-8(14-7(3)12)15-9(13)10(5,4)6(2)11/h5,8H,1-4H3/t5-,8-,10+/m1/s1
InChi Key
OYMZTORLGBISLR-RHFNHBFPSA-N
Origin
Bacterium/Streptomyces ramulosus
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $156

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    5 mg

    $577

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    Product Description

    Acetomycin is a γ-lactone microbial metabolite originally isolated from S. ramulosus that has anticancer activity.1 It inhibits proliferation of HCT-8 human colon and L1210 mouse leukemia cancer cells (IC50s = 1.5 and 2.2 µg/ml, respectively)

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mamber, S.W., Mitulski, J.D., Hamelehle, K.L., et al. Biological effects of acetomycin. I. Activity against tumor cells in vitro and in vivo. J. Antibiot. (Tokyo) 49(1), 73-76 (1987).