An internal standard for the quantification of valacyclovir
Related Products
Unlabeled Version(s)
23801L-Valacyclovir (hydrochloride)
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

L-Valacyclovir-d8 (hydrochloride)

Item No. 31479

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-valine-2,3,4,4,4,4′,4′,4′-d8, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester, monohydrochloride
CAS Number
1279033-32-7
Molecular Formula
C13H12D8N6O4 • HCl
Formula Weight
368.8
Purity
≥99% deuterated forms (d1-d8)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 3 mg/mlEthanol: InsolulePBS (pH 7.2): 10 mg/ml
SMILES
NC(NC1=C2N=CN1COCCOC([C@](N)([2H])C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=O)=NC2=O.Cl
InChi Code
InChI=1S/C13H20N6O4.ClH/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H/t8-;/m0./s1/i1D3,2D3,7D,8D;
InChi Key
ZCDDBUOENGJMLV-HVFXBKHYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 µg

    $196

    Add

    1 mg

    $370

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    L-Valacyclovir-d8 is intended for use as an internal standard for the quantification of L-valacyclovir (Item No. 23801) by GC- or LC-MS. L-Valacyclovir is an L-valyl prodrug form of the antiviral guanosine analog acyclovir (Item No. 14160). L-Valacyclovir inhibits herpes simplex virus type 1 (HSV-1) replication (IC50 = 0.84 µM in Vero cells).1 It is more potent than the stereoisomer D-valacyclovir but less potent than acyclovir in vitro, however, it is rapidly converted to acyclovir in vivo.2 Formulations containing L-valacyclovir have been used in the treatment of HSV-1 infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Beauchamp, L.M., Orr, G.F., de Miranda, P., et al. Amino acid ester prodrugs of acyclovir. Antivir. Chem. Chemother. 3(3), 157-164 (1992).

    2. Beutner, K.R. Valacyclovir: A review of its antiviral activity, pharmacokinetic properties, and clinical efficacy. Antiviral Res. 28(4), 281-290 (1995).