A mutagenic heterocyclic amine
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Product Categories

Product Type

Biochemicals

Research Area

Cancer

2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline

Item No. 31509

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,4-dimethyl-3H-imidazo[4,5-f]quinolin-2-amine
CAS Number
77094-11-2
Synonyms
  • MelQ
Molecular Formula
C12H12N4
Formula Weight
212.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: Slightly Soluble
SMILES
NC(N1C)=NC2=C1C(C)=CC3=C2C=CC=N3
InChi Code
InChI=1S/C12H12N4/c1-7-6-9-8(4-3-5-14-9)10-11(7)16(2)12(13)15-10/h3-6H,1-2H3,(H2,13,15)
InChi Key
GMGWMIJIGUYNAY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $49

    Add

    5 mg

    $213

    Add

    10 mg

    $376

    Add
    Cayman Chemical
    Visit Our Cancer Resource Center
    Find Tools & Resources to Study the Hallmarks of Cancer
    • Cancer cell signaling & regulation
    • Cancer metabolism
    • Tumor microenvironment
    EXPLORE NOW
    Product Description

    2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline is a mutagenic heterocyclic amine that has been found in cooked foods.1,2,3 It is mutagenic to S. typhimurium in the Ames test.3 Dietary administration of 2-amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline (0.03%) induces tumor formation in the Zymbal gland, oral cavity, and colon in male and female rats, the skin of male rats, and the mammary gland in female rats.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kato, T., Migita, H., Ohgaki, H., et al. Induction of tumors in the Zymbal gland, oral cavity, colon, skin and mammary gland of F344 rats by a mutagenic compound, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline. Carcinogenesis 19(3), 601-603 (1989).

    2. Johansson, M.A., and Jägerstad, M. Occurrence of mutagenic/carcinogenic heterocyclic amines in meat and fish products, including pan residues, prepared under domestic conditions. Carcinogenesis 15(8), 1511-1518 (1994).

    3. Nagao, M., Sato, S., and Sugimura, T. Mutagens produced by heating foods. The Maillard reaction in foods and nutrition 521-536 (1983).