An indole alkaloid with diverse biological activities
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Isomer(s)
31332Reserpiline
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Isoreserpiline

Item No. 31641

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(19α,20α)-16,17-didehydro-10,11-dimethoxy-19-methyl-oxayohimban-16-carboxylic acid, methyl ester
CAS Number
572-67-8
Synonyms
  • 3-Isoreserpilinic Acid, methyl ester
  • Neoreserpiline
Molecular Formula
C23H28N2O5
Formula Weight
412.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
SMILES
COC1=CC(N2)=C(C=C1OC)C3=C2[C@@]4([H])N(CC3)C[C@@]5([H])[C@H](C)OC=C(C(OC)=O)[C@@]5([H])C4
InChi Code
InChI=1S/C23H28N2O5/c1-12-16-10-25-6-5-13-15-8-20(27-2)21(28-3)9-18(15)24-22(13)19(25)7-14(16)17(11-30-12)23(26)29-4/h8-9,11-12,14,16,19,24H,5-7,10H2,1-4H3/t12-,14-,16-,19-/m0/s1
InChi Key
FGWJRZQNNZVCHR-HAHWVIBASA-N
Origin
Plant/Neisosperma poweri
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Isoreserpiline is an indole alkaloid that has been found in R. tetraphylla and has diverse biological activities.1,2 It has a synergistic effect on the antibacterial activity induced by nalidixic acid (Item No. 19807) in nalidixic acid-sensitive and -resistant strains of E. coli.2 It also reduces amphetamine-induced hyperactivity in mice when administered at a dose of 25 mg/kg.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gupta, S., Khanna, V.K., Maurya, A., et al. Bioactivity guided isolation of antipsychotic constituents from the leaves of Rauwolfia tetraphylla L. Fitoterapia 83(6), 1092-1099 (2012).

    2. Dwivedi, G.R., Gupta, S., Maurya, A., et al. Synergy potential of indole alkaloids and its derivative against drug-resistant Escherichia coli. Chem. Biol. Drug Des. 86(6), 1471-1481 (2015).