A drimane sesquiterpene
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Nanangenine F

Item No. 31658

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1R,4R,4aR,5R,8aS)-4-formyl-4,5-dihydroxy-3,4a,8,8-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl hexanoate
Molecular Formula
C21H34O5
Formula Weight
366.5
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
CC1(C)CC[C@@H](O)[C@@]2(C)[C@@]1([H])[C@H](OC(CCCCC)=O)C=C(C)[C@]2(O)C=O
InChi Code
InChI=1S/C21H34O5/c1-6-7-8-9-17(24)26-15-12-14(2)21(25,13-22)20(5)16(23)10-11-19(3,4)18(15)20/h12-13,15-16,18,23,25H,6-11H2,1-5H3/t15-,16-,18+,20+,21-/m1/s1
InChi Key
YBVXMQREWROXKL-XDISJUHXSA-N
Origin
Fungus/Aspergillus nanangensis
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    500 µg

    $236

    Add

    2.5 mg

    $876

    Add
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    Product Description

    Nanangenine F is a drimane sesquiterpene fungal metabolite that has been found in A. nanangensis.1 It is active against B. subtilis (IC50 = 78 µg/ml) and cytotoxic to NS-1, DU145, and MCF-7 cancer and NFF non-cancerous cells (IC50s = 49, 95, 49, and 84 µg/ml, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al. Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensis. Beilstein J. Org. Chem. 15, 2631-2643 (2019).