A building block
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L-Lysine lactam (hydrochloride)

Item No. 31685

Technical Information
Formal Name
(3S)-3-aminohexahydro-2H-azepin-2-one, monohydrochloride
CAS Number
26081-07-2
Synonyms
  • L-(-)-α-Amino-ε-caprolactam
  • (S)-3-Amino-2-azepanone
Molecular Formula
C6H12N2O • HCl
Formula Weight
Purity
≥95%
A crystalline solid
PBS (pH 7.2): 10 mg/ml
SMILES
N[C@@H]1C(NCCCC1)=O.Cl
InChi Code
InChI=1S/C6H12N2O.ClH/c7-5-3-1-2-4-8-6(5)9;/h5H,1-4,7H2,(H,8,9);1H/t5-;/m0./s1
InChi Key
LWXJCGXAYXXXRU-JEDNCBNOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    L-lysine lactam is a building block.1,2 It has been used in the synthesis of lysine sulfonamide HIV protease inhibitors, as well as bengamide derivatives with in vitro anticancer activity.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Stranix, B.R., Lavallée, J.-F., Sévigny, G., et alLysine sulfonamides as novel HIV-protease inhibitors: Nɛ-Acyl aromatic ɑ-amino acids. Bioorg. Med. Chem. Lett. 16(13), 3459-3462 (2006).

    2. Phi, T.D., Mai, H.D.T., Tran, V.H., et alDesign, synthesis and cytotoxicity of bengamide analogues and their epimers. Medchemcomm. 8(2), 445-451 (2016).