A red fluorescein dye and an inhibitor of dopamine reuptake
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Erythrosin B

Item No. 31722

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3′,6′-dihydroxy-2′,4′,5′,7′-tetraiodo-spiro[isobenzofuran-1(3H),9′-[9H]xanthen]-3-one, disodium salt
CAS Number
16423-68-0
Synonyms
  • Acid Red 51
  • Erythrosine
  • FD&C Red No. 3
Molecular Formula
C20H6I4O5 • 2Na
Formula Weight
879.9
Purity
≥85%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
540 nm
SMILES
O=C1OC2(C3=CC(I)=C(C(I)=C3OC4=C(C([O-])=C(C=C42)I)I)[O-])C5=C1C=CC=C5.[Na+].[Na+]
InChi Code
InChI=1S/C20H8I4O5.2Na/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20;;/h1-6,25-26H;;/q;2*+1/p-2
InChi Key
RAGZEDHHTPQLAI-UHFFFAOYSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    25 g

    $44

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    50 g

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    100 g

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    250 g

    $366

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    Product Description

    Erythrosin B is a red fluorescein dye and an inhibitor of dopamine reuptake (IC50 = 45 µM in rat brain synaptosomes).1,2,3 It has been used in the colorimetric and fluorescent determination of protein concentrations in vitro.1,2 Formulations containing erythrosine B have been used as color additives in food and pharmaceutical preparations.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ma, C.Q., Li, K.A., and Tong, S.Y. Determination of proteins by fluorescence quenching of erythrosin B. Anal. Chim. Acta 333(1-2), 83-88 (1996).

    2. Soedjak, H.S. Colorimetric micromethod for protein determination with erythrosin B. Anal. Biochem. 220(1), 142-148 (1994).

    3. Lafferman, J.A., and Silbergeld, E.K. Erythrosin B inhibits dopamine transport in rat caudate synaptosomes. Science 205(4404), 410-412 (1979).