An oxidized dimeric form of cysteine
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L-Cystine

Item No. 31727

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
56-89-3
Synonyms
  • (–)-Cystine
  • NSC 13203
Molecular Formula
C6H12N2O4S2
Formula Weight
240.3
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
SMILES
OC([C@@H](N)CSSC[C@H](N)C(O)=O)=O
InChi Code
InChI=1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1
InChi Key
LEVWYRKDKASIDU-IMJSIDKUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 g

    $54

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    250 g

    $86

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    500 g

    $158

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    Product Description

    L-Cystine is a dimeric form of cysteine that is formed by the covalent oxidative linkage of two cysteine residues.1 It accumulates in the lysosomes of patients with cystinosis, an autosomal recessive lysosomal storage disorder, and is associated with renal Fanconi syndrome and loss of glomerular function.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Appenzeller-Herzog, C., and Riemer, J. Techniques to monitor disulfide bond formation and the reduction potential of cysteine–cystine couples in vitro and in vivo. Oxidative folding of proteins: Basic principles, cellular regulation and engineering 34-51 (2018).

    2. Elmonem, M.A., Veys, K.R., Soliman, N.A., et al. Cystinosis: A review. Orphanet J. Rare Dis. 11, 47 (2016).