A cyclodepsipeptide with diverse biological activities
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Beauvericin A

Item No. 31773

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3S,6R,9S,12R,15S,18R)-4,10,16-trimethyl-6,12-bis(1-methylethyl)-18-[(1S)-1-methylpropyl]-3,9,15-tris(phenylmethyl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
CAS Number
165467-50-5
Molecular Formula
C46H59N3O9
Formula Weight
798.0
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: solubleMethanol: soluble
SMILES
CN(C([C@@](OC([C@@H](N(C([C@H](OC([C@@H](N(C([C@H](OC1=O)C(C)C)=O)C)CC2=CC=CC=C2)=O)C(C)C)=O)C)CC3=CC=CC=C3)=O)([H])[C@@H](C)CC)=O)[C@H]1CC4=CC=CC=C4
InChi Code
InChI=1S/C46H59N3O9/c1-10-31(6)40-43(52)49(9)36(27-33-22-16-12-17-23-33)45(54)57-38(29(2)3)41(50)47(7)35(26-32-20-14-11-15-21-32)44(53)56-39(30(4)5)42(51)48(8)37(46(55)58-40)28-34-24-18-13-19-25-34/h11-25,29-31,35-40H,10,26-28H2,1-9H3/t31-,35-,36-,37-,38+,39+,40+/m0/s1
InChi Key
JQUGYVKOYKGIRB-PGVJVUNISA-N
Origin
Fungus/Beauveria bassiana
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 µg

    $134

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    Cayman Chemical
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    Product Description

    Beauvericin A is a cyclodepsipeptide and derivative of beauvericin (Item No. 11426) originally isolated from B. bassiana that has diverse biological activities.1,2,3 It is active against M. tuberculosis (MIC = 25 µg/ml) and P. falciparum (IC50 = 12 µg/ml).2 Beauvericin A is toxic to brine shrimp (LD100 = 32 µg/ml).3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gupta, S., Montillor, C., and Hwang, Y.-S. Isolation of Novel Beauvericin Analogues from the Fungus Beauveria bassiana. J. Nat. Prod. 58(5), 733-738 (1995).

    2. Nilanonta, C., Isaka, M., Kittakoop, P., et al. Antimycobacterial and antiplasmodial cyclodepsipeptides from the insect pathogenic fungus Paecilomyces tenuipes BCC 1614. Planta Med. 66(8), 756-758 (2000).

    3. Shi, S., Li, Y., Ming, Y., et al. Biological activity and chemical composition of the endophytic fungus Fusarium sp. TP-G1 obtained from the root of Dendrobium officinale Kimura et Migo. Rec. Nat. Prod. 12(6), 549-556 (2018).