A microbial metabolite with antibacterial and antifungal activities
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

(–)-Mycousnine

Item No. 31784

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(4aR,9bS)-2,6-diacetyl-4a,9b-dihydro-3,7,9-trihydroxy-4a-methoxy-8,9b-dimethyl-1(4H)-dibenzofuranone
CAS Number
77480-55-8
Synonyms
  • Mycousunin
Molecular Formula
C19H20O8
Formula Weight
376.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
λmax
227, 285 nm
SMILES
CO[C@@]12[C@@](C3=C(O)C(C)=C(O)C(C(C)=O)=C3O1)(C(C(C(C)=O)=C(C2)O)=O)C
InChi Code
InChI=1S/C19H20O8/c1-7-14(23)12(9(3)21)16-13(15(7)24)18(4)17(25)11(8(2)20)10(22)6-19(18,26-5)27-16/h22-24H,6H2,1-5H3/t18-,19+/m0/s1
InChi Key
WWSUFZCWOJULTK-RBUKOAKNSA-N
Origin
Fungus/Unidentified sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $267

    Add

    5 mg

    $1,062

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    (–)-Mycousnine is a microbial metabolite and derivative of usnic acid (Item No. 22585) originally isolated from M. nawae that has antibacterial and antifungal activities.1,2 It is active against the Gram-positive bacteria B. subtilis, K. rhizophila, and S. aureus (MICs = 4, 8, and 4 g/ml, respectively) but not the Gram-negative bacteria E. coli, S. typhimurium, and K. pneumoniae (MICs = >128 g/ml for all).2 (–)-Mycousnine is also active against the fungi T. mentagrophytes, T. rubrum, and C. albicans (MICs = 25, 25, and 100 µg/ml, respectively).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sassa, T., and Igarashi, M. Structures of (−)-mycousnine, (+)-isomycousnine and (+)-oxymycousnine, new usnic acid derivatives from phytopathogenic Mycosphaerella nawae. Agric. BioI. Chem. 54(9), 2231-2237 (1990).

    2. Lee, J., Lee, J., Kim, G.J., et al. Mycousfurans A and B, antibacterial usnic acid congeners from the fungus Mycosphaerella sp., isolated from a marine sediment. Mar. Drugs 17(7), 422 (2019).