For immunochemical detection of CEA
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CEA Rabbit Monoclonal Antibody (Clone RM326)

Item No. 32264

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Carcinoembryonic Antigen
Immunogen
Native CEA protein purified from human liver tissue
Clone Designation
RM326
Formulation (Request formulation change)
100 µl of protein A-affinity purified monoclonal antibody
Storage Buffer
PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide
Host
Rabbit
Isotype
IgG
Applications
ELISA, IHC, WB
Cross Reactivity
(+) CEA
Species Reactivity
(+) Human
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    100 µl

    $411

    Add
    Cayman Chemical
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    Product Description

    Carcinoembryonic antigen (CEA) is a glycoprotein and member of the immunoglobulin (Ig) superfamily with a role in cell adhesion.1,2,3 It is composed of an N-terminal Ig variable domain-like (IgV-like) domain, six Ig constant 2-like (IgC2-like) domains, and a glycosylphosphatidylinositol (GPI) anchor that is attached to the cell membrane.1 CEA is expressed during fetal development but is absent by birth and is not present in adults.3 However, CEA is expressed by human colon carcinomas where it functions as a ligand for E-selectin and L-selectin that is essential to cancer metastasis. Levels of CEA are positively correlated with risk of recurrence and death in patients with non-small cell lung cancer (NSCLC). Cayman’s CEA Rabbit Monoclonal Antibody (Clone RM326) can be used for ELISA, immunohistochemistry (IHC), and Western blot (WB) applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Duffy, M.J. Carcinoembryonic antigen as a marker for colorectal cancer: Is it clinically useful? Clin. Chem. 47(4), 624-630 (2001).

    2. Benchimol, S., Fuks, A., Jothy, S., et al. Carcinoembryonic antigen, a human tumor marker functions as an intercellular adhesion molecule. Cell 57, 327-334 (1989).

    3. Grunnet, M., and Sorensen, J.B. Carcinoembryonic antigen (CEA) as tumor marker in lung cancer. Lung Cancer 76(2), 138-143 (2012).