For immunochemical detection of MyoD1
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MyoD1 Rabbit Monoclonal Antibody (Clone RM369)

Item No. 32294

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Myf3
  • Myoblast Determination Protein 1
  • Myogenic Determination Factor 1
  • Myogenic Differentiation 1
  • Myogenic Factor 3
Immunogen
Peptide corresponding to residues near the N-terminus of human MyoD1
Clone Designation
RM369
Formulation (Request formulation change)
100 µl of protein A-affinity purified monoclonal antibody
Storage Buffer
PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide
Host
Rabbit
Isotype
IgG
Applications
IHC, WB
Cross Reactivity
(+) MyoD1
Species Reactivity
(+) Human(+) Mouse(+) Rat
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    100 µl

    $411

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    Product Description

    Myogenic determination factor 1 (MyoD1) is a transcription factor and member of the myogenic regulatory factor (MRF) protein family with a role in muscle differentiation.1,2 It is composed of an unstructured N-terminus, a central basic helix-loop-helix domain with a cysteine/histidine domain located at its N-terminus, and a serine/threonine-rich domain proximal to an unstructured C-terminal tail.2,3 MyoD1 is expressed exclusively in skeletal muscle and localized to the nucleus where it binds E-box sequences found in promoters and enhancer regions of muscle-specific genes to regulate transcription during development or in response to skeletal muscle injury. Cayman’s MyoD1 Rabbit Monoclonal Antibody (Clone RM369) can be used for immunohistochemistry (IHC) and Western blot (WB) applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Folpe, A.L. MyoD1 and myogenin expression in human neoplasia: A review and update. Adv. Anat. Pathol. 9(3), 198-203 (2002).

    2. Asfour, H.A., Allouh, M.Z., and Said, R.S. Myogenic regulatory factors: The orchestrators of myogenesis after 30 years of discovery. Exp. Biol. Med. (Maywood) 243(2), 118-128 (2018).

    3. Talbot, J., and Maves, L. Skeletal muscle fiber type: Using insights from muscle developmental biology to dissect targets for susceptibility and resistance to muscle disease. Wiley Interdiscip. Rev. Dev. Biol. 5(4), 518-534 (2016).