For immunochemical detection of H. pylori
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Helicobacter pylori Rabbit Monoclonal Antibody (RM400)

Item No. 32325

Technical Information
Synonyms
  • H. pylori
Immunogen
Proteins purified from H. pylori
Clone Designation
RM400
100 µl of protein A-affinity purified monoclonal antibody
Storage Buffer
PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide
Host
Rabbit
Isotype
IgG
Applications
IHC
Cross Reactivity
(+) H. pylori
Species Reactivity
(+) H. pylori
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Helicobacter pylori (H. pylori) is a Gram-negative bacterium that can infect and colonize the stomach.1 Transmission of H. pylori can occur directly through person-to-person contact, as well as through contaminated drinking water, raw vegetables, or animal milk.2 H. pylori infection can lead to chronic gastritis, stomach inflammation and oxidative stress, peptic ulcer disease, and gastric cancer.1 It is considered an oncogenic agent and, although a low percentage of patients infected with H. pylori develop stomach cancer, it is responsible for the majority of stomach cancers. In mouse models of H. pylori infection, antibiotics can reduce and prevent gastritis and pre-malignant changes. Cayman’s Helicobacter pylori Rabbit Monoclonal Antibody (RM400) can be used for immunohistochemistry (IHC).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chang, A.H., and Parsonnet, J. Role of bacteria in oncogenesis. Clin. Microbiol. Rev. 23(4), 837-857 (2010).

    2. Mezmale, L., Coelho, L.G., Bordin, D., et al. Review: Epidemiology of Helicobacter pylori. Helicobacter 25(Suppl 1), e12734 (2020).