For immunochemical detection of OMP
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Helicobacter pylori OMP Rabbit Monoclonal Antibody (Clone RM410)

Item No. 32341

Technical Information
Synonyms
  • Outer Membrane Protein
Immunogen
Proteins purified from H. pylori
Clone Designation
RM410
100 µg of protein A-affinity purified monoclonal antibody
Storage Buffer
PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide
Host
Rabbit
Isotype
IgG
Applications
ELISA
Cross Reactivity
(+) OMP(-) CagA(-) Urease(-) HP-NAP
Species Reactivity
(+) H. pylori
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    Add

    Cayman Chemical
    Visit Our Cancer Resource Center
    Find Tools & Resources to Study the Hallmarks of Cancer
    • Cancer cell signaling & regulation
    • Cancer metabolism
    • Tumor microenvironment
    EXPLORE NOW
    Product Description

    Helicobacter pylori is a Gram-negative bacterium that can infect and colonize the stomach, leading to chronic gastritis, stomach inflammation and oxidative stress, peptic ulcer disease, and gastric cancer.1 H. pylori expresses greater than 30 outer membrane proteins (OMPs) on the surface of its outer membrane encoded by two gene families, helicobacter outer membrane porins (hop) and hop-related (hor).2,3,4 OMPs have roles in H. pylori attachment and colonization, the expression of pathogenic factors, antibiotic resistance, and maintenance of the outer membrane integrity. Cayman’s Helicobacter pylori OMP Rabbit Monoclonal Antibody (Clone RM410) can be used for ELISA. The antibody recognizes a 23 kDa OMP.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chang, A.H., and Parsonnet, J. Role of bacteria in oncogenesis. Clin. Microbiol. Rev. 23(4), 837-857 (2010).

    2. Matsuo, Y., Kido, Y., and Yamaoka, Y. Helicobacter pylori outer membrane protein-related pathogenesis. Toxins (Basel) 9(3), 101 (2017).

    3. Xu, C., Soyfoo, D.M., Wu, Y., et al. Virulence of Helicobacter pylori outer membrane proteins: An updated review. Eur. J. Clin. Microbiol. Infect. Dis. 39(10), 1821-1830 (2020).

    4. Odenbreit, S., Swoboda, K., Barwig, I., et al. Outer membrane protein expression profile in Helicobacter pylori clinical isolates. Infect. Immun. 77(9), 3782-3790 (2009).