A fluorescent probe for hypochlorous acid
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MXS

Item No. 32726

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(E)-N-ethyl-N-(6-methoxy-9-(4-(methylthio)styryl)-3H-xanthen-3-ylidene)ethanaminium
Molecular Formula
C27H28NO2S
Formula Weight
430.6
Purity
≥90%
Emission
654 nm
Excitation
530 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:5): 0.16 mg/mlEthanol: slightly soluble
λmax
230, 296, 530 nm
SMILES
CSC(C=C1)=CC=C1/C=C/C2=C3C(OC4=C2C=CC(OC)=C4)=C/C(C=C3)=[N+](CC)\CC
InChi Code
InChI=1S/C27H28NO2S/c1-5-28(6-2)20-10-15-24-23(14-9-19-7-12-22(31-4)13-8-19)25-16-11-21(29-3)18-27(25)30-26(24)17-20/h7-18H,5-6H2,1-4H3/q+1/b14-9+
InChi Key
VYLRQRHDXQDQDA-NTEUORMPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $129

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    5 mg

    $303

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    10 mg

    $469

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    Product Description

    MXS is a mitochondria-targeted fluorescent probe for hypochlorous acid (HOCl).1 It selectively fluoresces in the presence of OCl- over O2, H2O2, NO, NO2-, NO3-, O2-, ONOO-, and •OH when used at a concentration of 10 µM. MXS has been used to monitor real-time mitochondrial HOCl levels in living cells. It displays excitation/emission maxima of 530/654 nm, respectively.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gong, J., Liu, C., Cai, S., et al. Novel near-infrared fluorescent probe with a large Stokes shift for sensing hypochlorous acid in mitochondria. Org. Biomol. Chem. 18(38), 7656-7662 (2020).