A lipophilic hyponitrite radical initiator
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DTUN

Item No. 32742

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(E)-1,2-bis((2-methyldecan-2-yl)oxy)diazene
Molecular Formula
C22H46N2O2
Formula Weight
370.6
Formulation (Request formulation change)
A film
Solubility(Learn about Variance in Solubility)
Ethanol: 50 mg/ml
λmax
227 nm
SMILES
CC(O/N=N/OC(CCCCCCCC)(C)C)(C)CCCCCCCC
InChi Code
InChI=1S/C22H46N2O2/c1-7-9-11-13-15-17-19-21(3,4)25-23-24-26-22(5,6)20-18-16-14-12-10-8-2/h7-20H2,1-6H3/b24-23+
InChi Key
PMZYNORKCNTVQB-WCWDXBQESA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $82

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    1 mg

    $154

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    5 mg

    $647

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    10 mg

    $1,051

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    Product Description

    DTUN is a lipophilic hyponitrite radical initiator.1 It initiates co-autoxidation of STY-BODIPY-embedded egg phosphatidylcholine liposomes when used at a concentration of 0.2 mM. DTUN has been used in fluorescence-enabled inhibited autoxidation (FENIX) assays for the development of ferroptosis inhibitors and the study of antioxidants in lipid membranes.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Shah, R., Farmer, L.A., Zilka, O., et al. Beyond DPPH: Use of fluorescence-enabled inhibited autoxidation to predict oxidative cell death rescue. Cell Chem. Biol. 26(11), 1594-1607 (2019).

    2. Soula, M., Weber, R.A., Zilka, O., et al. Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers. Nat. Chem. Biol. 16(12), 1351-1360 (2020).