A fungal metabolite
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Aureonitol

Item No. 32925

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2S,3R,4S)-2-(1,3-butadien-1-yl)tetrahydro-4-(1,3-pentadien-1-yl)-3-furanol
CAS Number
71774-51-1
Molecular Formula
C13H18O2
Formula Weight
206.3
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
C/C=C/C=C/[C@H]1CO[C@@H](/C=C/C=C)[C@@H]1O
InChi Code
InChI=1S/C13H18O2/c1-3-5-7-8-11-10-15-12(13(11)14)9-6-4-2/h3-9,11-14H,2,10H2,1H3/b5-3+,8-7+,9-6+/t11-,12-,13+/m0/s1
InChi Key
DTLKTHCXEMHTIQ-DBCNHVMASA-N
Origin
Fungus/Chaetomium sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    100 µg

    $156

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    500 µg

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    Product Description

    Aureonitol is a fungal metabolite that has been found in Chaetomium and has antiviral activity.1 It inhibits replication of the influenza A subtype H3N2 with an EC50 value of 30 nM at a multiplicity of infection (MOI) of 0.01. It also inhibits replication of laboratory-adapted and clinical isolates of H3N2 (EC50s = 100 and 312 nM, respectively), as well as clinical isolates of the influenza A subtype H1N1 (EC50 = 417 nM). Aureonitol inhibits hemagglutination activity of H3N2 and H1N1.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sacramento, C.Q., Marttorelli, A., Fintelman-Rodrigues, N., et al. Aureonitol, a fungi-derived tetrahydrofuran, inhibits influenza replication by targeting its surface glycoprotein hemagglutinin. PLoS One 10(10), e0139236 (2015).