A fungal metabolite
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Bassianin

Item No. 32926

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-[(2E,4E,6E)-6,8-dimethyl-1-oxo-2,4,6-decatrienyl]-1,4-dihydroxy-5-(4-hydroxyphenyl)-2(1H)-pyridinone
CAS Number
54278-73-8
Molecular Formula
C23H25NO5
Formula Weight
395.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: solubleMethanol: soluble
SMILES
OC(C(C1=CC=C(C=C1)O)=CN2O)=C(C(/C=C/C=C/C(C)=C/C(C)CC)=O)C2=O
InChi Code
InChI=1S/C23H25NO5/c1-4-15(2)13-16(3)7-5-6-8-20(26)21-22(27)19(14-24(29)23(21)28)17-9-11-18(25)12-10-17/h5-15,25,27,29H,4H2,1-3H3/b7-5+,8-6+,16-13+
InChi Key
LJUJZTYMRBJWDZ-ZDNNFFFZSA-N
Origin
Fungus/Beauveria bassiana
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 µg

    $214

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    500 µg

    $797

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    Product Description

    Bassianin is a fungal metabolite that has been found in Beauveria.1,2 It inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in equine erythrocyte ghosts by 81, 58, and 23%, respectively, when used at a concentration of 200 µg/ml.1 Bassianin is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.91 and 12.12 µM, respectively.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Jeffs, L.B., and Khachatourians, G.G. Toxic properties of Beauveria pigments on erythrocyte membranes. Toxicon. 35(8), 1351-1356 (1997).

    2. Arboleda Valencia, J.W., Gaitán Bustamante, A.L., Jiménez, A.V., et al. Cytotoxic activity of fungal metabolites from the pathogenic fungus Beauveria bassiana: An intraspecific evaluation of beauvericin production. Curr. Microbiol. 63(3), 306-312 (2011).