A hemostatic agent
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Product Categories

Product Type

Biochemicals

Research Area

Cardiovascular System
Blood
Coagulation & Hemostasis

Carbazochrome

Item No. 32951

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(1,2,3,6-tetrahydro-3-hydroxy-1-methyl-6-oxo-5H-indol-5-ylidene)-hydrazinecarboxamide
CAS Number
69-81-8
Synonyms
  • Adrenochrome Monosemicarbazone
  • Adrenochrome Semicarbazone
  • NSC 73742
Molecular Formula
C10H12N4O3
Formula Weight
236.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 1 mg/mlDMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml
λmax
358 nm
SMILES
O=C(NN=C1C=C2C(N(CC2O)C)=CC1=O)N
InChi Code
InChI=1S/C10H12N4O3/c1-14-4-9(16)5-2-6(12-13-10(11)17)8(15)3-7(5)14/h2-3,9,16H,4H2,1H3,(H3,11,13,17)
InChi Key
XSXCZNVKFKNLPR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 g

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    50 g

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    100 g

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    Product Description

    Carbazochrome is a hemostatic agent.1,2 In vivo, carbazochrome (0.1 mg/kg) reduces blood loss by 45% in a mouse model of traumatic hemorrhage.1 Topical administration of carbazochrome induces blood coagulation at back wound sites in mice.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Keith, J.H., Keith, W.W., and Nelson, M.H. Effects of adrenochrome semicarbazone on blood loss in the mouse. J. Pharm. Sci. 56(8), 997-1001 (1967).

    2. Mukherjee, D., and Banthia, A.K. Preparation of adrenochrome hydrogel patch, gel, ointment, and the comparison of their blood coagulating and wound healing capability. Mater. Manuf. Process. 21(3), 297-301 (2006).