An alkaloid
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(±)-Salsolidine

Item No. 32953

Technical Information
Formal Name
1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-isoquinoline
CAS Number
5784-74-7
Synonyms
  • N-Norcarnegine
Molecular Formula
C12H17NO2
Formula Weight
Purity
≥95%
Formulation
A crystalline solid
DMF: 30 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
COC1=C(C=C2C(C(C)NCC2)=C1)OC
InChi Code
InChI=1S/C12H17NO2/c1-8-10-7-12(15-3)11(14-2)6-9(10)4-5-13-8/h6-8,13H,4-5H2,1-3H3
InChi Key
HMYJLVDKPJHJCF-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    (±)-Salsolidine is an alkaloid that has been found in H. articulatum.1 It inhibits catechol-O-methyltransferase (COMT; Ki = 190 µM).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. El-Shazly, A., and Wink, M. Tetrahydroisoquinoline and β-carboline alkaloids from Haloxylon articulatum (Cav.) Bunge (Chenopodiaceae). Z. Naturforsch C. J. Biosci. 58(7-8), 477-480 (2003).

    2. Sanft, K., and Thomas, H. Competitive inhibition of catechol-O-methyltransferase by the tetrahydroisoquinoline alkaloids salsolidine and 1-carboxysalsoline. Z. Naturforsch C. J. Biosci. 44(1-2), 173-176 (1989).