A bacterial metabolite with diverse biological activities
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Carbazomycin D

Item No. 33091

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,4,6-trimethoxy-1,2-dimethyl-9H-carbazole
CAS Number
108073-63-8
Molecular Formula
C17H19NO3
Formula Weight
285.3
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
COC1=C(C)C(C)=C2NC3=CC=C(OC)C=C3C2=C1OC
InChi Code
InChI=1S/C17H19NO3/c1-9-10(2)16(20-4)17(21-5)14-12-8-11(19-3)6-7-13(12)18-15(9)14/h6-8,18H,1-5H3
InChi Key
AVVRXRXZUJFTHU-UHFFFAOYSA-N
Origin
Bacterium/Streptomyces sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 µg

    $208

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    500 µg

    $777

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    Product Description

    Carbazomycin D is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities.1,2 It is active against the fungi T. asteroides and T. mentagrophytes (MIC = 100 µg/ml for both) and the bacterium M. tuberculosis (IC50 = 25 µg/ml). Carbazomycin D is cytotoxic to MCF-7, KB, NCI H187, and Vero cells (IC50s = 21.3, 33.2, 12.9, and 34.3 µg/ml, respectively).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Naid, T., Kitahara, T., Kaneda, M., et al. Carbazomycins C, D, E and F, minor components of the carbazomycin complex. J. Antibiot. (Tokyo) 40(2), 157-164 (1987).

    2. Intaraudom, C., Rachtawee, P., Suvannakad, R., et al. Antimalarial and antituberculosis substances from Streptomyces sp. BCC26924. Tetrahedron 67(39), 7593-7597 (2011).