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N-Pyrrolidino Etonitazene

Item No. 33169

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Etonitazepyne
Technical Information
Formal Name
2-[(4-ethoxyphenyl)methyl]-5-nitro-1-[2-(1-pyrrolidinyl)ethyl]-1H-benzimidazole
CAS Number
2785346-75-8
Molecular Formula
C22H26N4O3
Formula Weight
394.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: 10 mg/mlDMF: 30 mg/mlDMSO: 1 mg/mlEthanol: 5 mg/mlMethanol: 10 mg/ml
λmax
242 nm
SMILES
CCOC(C=C1)=CC=C1CC2=NC3=CC([N+]([O-])=O)=CC=C3N2CCN4CCCC4
InChi Code
InChI=1S/C22H26N4O3/c1-2-29-19-8-5-17(6-9-19)15-22-23-20-16-18(26(27)28)7-10-21(20)25(22)14-13-24-11-3-4-12-24/h5-10,16H,2-4,11-15H2,1H3
InChi Key
LQZWZCJCEPUKCJ-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    N-Pyrrolidino etonitazene (Item No. 33169) is an analytical reference standard categorized as an opioid.1 N-Pyrrolidino etonitazene has been associated with overdose fatalities as the cause of death or in combination with other compounds. N-Pyrrolidino etonitazene is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vandeputte, M.M., Krotulski, A.J., Walther, D., et al. Pharmacological evaluation and forensic case series of N‑pyrrolidino etonitazene (etonitazepyne), a newly emerging 2‑benzylbenzimidazole ‘nitazene’ synthetic opioid. Arch. Toxicol. 96, 1845-1863 (2022).

    Product Citations

    Tsai, M.-H.M., Chen, L., Baumann, M.H., et al. In Vitro Functional Profiling of Fentanyl and Nitazene Analogs at the μ-Opioid Receptor Reveals High Efficacy for Gi Protein Signaling. ACS Chem. Neurosci. 15(4), 854-867 (2024).

    Vandeputte, M.M., Krotulski, A.J., Walther, D., et al. Pharmacological evaluation and forensic case series of N‑pyrrolidino etonitazene (etonitazepyne), a newly emerging 2‑benzylbenzimidazole ‘nitazene’ synthetic opioid. Arch. Toxicol. 96, 1845-1863 (2022).