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Gadoleic acid is a monounsaturated fatty acid.1,2 It inhibits the dsDNA binding activity of p53 when used at a concentration of 1.2 nM.1 Hepatic levels of gadoleic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet and increased in rats fed a high-cholesterol diet.2
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1. The inhibitory action of long-
2. Effects of dietary fatty acids and cholesterol excess on liver injury: A lipidomic approach. Redox Biol. 9, 296-305 (2016).