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Isosorbide is a 1,4:3,6-dianhydrohexitol that can be derived from glucose.1 It has been used in the synthesis of the nitric oxide (NO) donors isosorbide mono- and dinitrate, which have vasodilatory activity. Isosorbide has also been used as a monomer or building block in the synthesis of various polymers and functional materials, respectively.
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1. Isosorbide as a renewable platform chemical for versatile applications--