A bacterial metabolite
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Conglobatin C1

Item No. 33256

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3E,7S,11E,15S-tetramethyl-8S,16S-bis(5-oxazolylmethyl)-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione
CAS Number
2673270-37-4
Molecular Formula
C26H34N2O6
Formula Weight
470.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleMethanol: Soluble
SMILES
C/C(C(O[C@@H](CC1=CN=CO1)[C@@H](C)CC/C=C2\C)=O)=C\CC[C@H](C)[C@H](CC3=CN=CO3)OC2=O
InChi Code
InChI=1S/C26H34N2O6/c1-17-7-5-9-19(3)26(30)34-24(12-22-14-28-16-32-22)18(2)8-6-10-20(4)25(29)33-23(17)11-21-13-27-15-31-21/h9-10,13-18,23-24H,5-8,11-12H2,1-4H3/b19-9+,20-10+/t17-,18-,23-,24-/m0/s1
InChi Key
LVEHBOBGUJZZBO-KDTLMUGASA-N
Origin
Bacterium/Streptomyces conglobatus
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $214

    Add

    5 mg

    $797

    Add
    Cayman Chemical
    Visit Our Cancer Resource Center
    Find Tools & Resources to Study the Hallmarks of Cancer
    • Cancer cell signaling & regulation
    • Cancer metabolism
    • Tumor microenvironment
    EXPLORE NOW
    Product Description

    Conglobatin C1 is a bacterial metabolite that has been found in Streptomyces MST-91080 and has anticancer activity.1 It is cytotoxic to NS-1 mouse myeloma cells (IC50 = 1.05 µg/ml) but not NFF human fibroblasts (IC50 = >100 µg/ml).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lacey, H.J., Booth, T.J., Vuong, D., et al. Conglobatins B-E: Cytotoxic analogues of the C2-symmetric macrodiolide conglobatin. J. Antibiot. (Tokyo) 73(11), 756-765 (2020).