An azo dye
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Sunset Yellow FCF

Item No. 33257

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-hydroxy-5-[2-(4-sulfophenyl)diazenyl]-2-naphthalenesulfonic acid, disodium salt
CAS Number
2783-94-0
Synonyms
  • C.I. 15985
  • 1351 Yellow
  • 1899 Yellow
  • Orange Yellow S
Molecular Formula
C16H10N2O7S2 • 2Na
Formula Weight
452.4
Purity
≥85%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 30 mg/mlEthanol: Slightly solublePBS (pH 7.2): 10 mg/ml
λmax
214, 235, 312, 479 nm
SMILES
O=S([O-])(C1=CC=C(C=C1)N=NC2=C(C=CC3=CC(S(=O)([O-])=O)=CC=C32)O)=O.[Na+].[Na+]
InChi Code
InChI=1S/C16H12N2O7S2.2Na/c19-15-8-1-10-9-13(27(23,24)25)6-7-14(10)16(15)18-17-11-2-4-12(5-3-11)26(20,21)22;;/h1-9,19H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2
InChi Key
OIQPTROHQCGFEF-UHFFFAOYSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Cayman Chemical
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    Product Description

    Sunset yellow FCF is an azo dye.1 It displays an absorption maximum of 480 nm.1,2 It reduces LPS-induced proliferation of isolated mouse splenocytes, as well as inhibits proliferation of isolated mouse splenocytes in an allogenic mixed lymphocyte reaction when used at a concentration of 250 µg/ml.3 Sunset yellow FCF (0.325 mg/kg) induces chromosomal aberrations in somatic and germ cells and morphological abnormalities in sperm in mice, but it is not genotoxic in a micronucleus gut assay in mice when administered at doses up to 2,000 mg/kg.4 Formulations containing sunset yellow FCF have been used as colorants in food and cosmetic preparations.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ghoneim, M.M., El-Desoky, H.S., and Zidan, N.M. Electro-Fenton oxidation of Sunset Yellow FCF azo-dye in aqueous solutions. Desalination 274(1-3), 22-30 (2011).

    2. Sabnis, R.W. Handbook of biological dyes and stains: Synthesis and industrial applications. (2010).

    3. Yadav, A., Kumar, A., Tripathi, A., et al. Sunset yellow FCF, a permitted food dye, alters functional responses of splenocytes at non-cytotoxic dose. Toxicol. Lett. 217(3), 197-204 (2013).

    4. Sayed, H.M., Fouad, D., Ataya, F.S., et al. The modifying effect of selenium and vitamins A, C, and E on the genotoxicity induced by sunset yellow in male mice. Mutat. Res. 744(2), 145-153 (2012).